| Gene Information | |
|---|---|
| Gene Name | SLC26A7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 656 |
| Protein Names | Anion exchange transporter (Solute carrier family 26 member 7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000147606 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q8TE54 |
| Gene Card | SLC26A7 |
| Uniprot ID | Q8TE54 |
| Pfam | PF01740; PF00916 |
| In ASD | no |
| Allosteric Prediction | no (-0.747007433) |
| Ortholog in Animals | Alpaca_ SLC26A7 ( ortholog_one2one ) Dog_ SLC26A7 ( ortholog_one2one ) GuineaPig_ SLC26A7 ( ortholog_one2one ) Macaque_ SLC26A7 ( ortholog_one2one ) Mouse_ Slc26a7 ( ortholog_one2one ) Pig_ SLC26A7 ( ortholog_one2one ) Rat_ Slc26a7 ( ortholog_one2one ) Rabbit_ SLC26A7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC26A6, SLC26A3, SLC26A5, SLC26A4, SLC26A8, SLC26A1, SLC26A2, SLC26A9, SLC26A11 |
| Tissue | thyroid, placenta, kidney |
| Tissue Specificity | Expressed in tonsillar high endothelial venule endothelial cells (HEVEC), placenta and in testis, expressed in a subgroup of basal cells in the epididymal ducts. {ECO:0000269|PubMed:11829495, ECO:0000269|PubMed:11834742, ECO:0000269|PubMed:15956810, ECO:0000269|PubMed:17504921}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16912250 rs34921316 |
| Subcellular location [CC] | Recycling endosome membrane {ECO:0000269|PubMed:16524946}; Multi-pass membrane protein {ECO:0000269|PubMed:16524946}. Note=Expressed in the cytoplasm in recycling endosomes of medullary collecting duct cells and in acid-secreting gastric parietal cells. Targeted to the basolateral membrane in hypertonicity and potassium depletion. {ECO:0000269|PubMed:16524946}. |
| Mouse PG classification | NA |
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