Gene Information
Gene NameM6PR
OrganismHomo sapiens (Human)
Gene Length277
Protein NamesCation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46)
Target Namecation-dependent mannose-6-phosphate receptor
Target TypeNA
Gene Age454 ( ENSG00000003056 )
Evolutionary StageOpisthokonta
AlphaFoldDBP20645
Gene CardM6PR
Uniprot IDP20645
PfamPF02157
In ASDno
Allosteric Predictionno (-0.212049841)
Ortholog in AnimalsAlpaca_ M6PR ( ortholog_one2one )
Dog_ M6PR ( ortholog_one2one )
GuineaPig_ M6PR ( ortholog_one2one )
Macaque_ M6PR ( ortholog_one2one )
Mouse_ M6pr ( ortholog_one2one )
Pig_ M6PR ( ortholog_one2one )
Rat_ M6pr ( ortholog_one2many )
Rabbit_ M6PR ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1JUQ  (X-ray  2.20A 
DBSNP NA 
Subcellular location [CC]Lysosome membrane;
Single-pass type I membrane protein.
Mouse PG classificationNA
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