| Gene Information | |
|---|---|
| Gene Name | EDEM2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 578 |
| Protein Names | ER degradation-enhancing alpha-mannosidase-like protein 2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000088298 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BV94 |
| Gene Card | EDEM2 |
| Uniprot ID | Q9BV94 |
| Pfam | PF01532 |
| In ASD | no |
| Allosteric Prediction | no (-1.216145814) |
| Ortholog in Animals | Alpaca_ EDEM2 ( ortholog_one2one ) Dog_ EDEM2 ( ortholog_one2one ) GuineaPig_ EDEM2 ( ortholog_one2one ) Macaque_ EDEM2 ( ortholog_one2one ) Mouse_ Edem2 ( ortholog_one2one ) Pig_ EDEM2 ( ortholog_one2one ) Rat_ Edem2 ( ortholog_one2one ) Rabbit_ EDEM2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MAN1A2, MAN1A1, MAN1B1, EDEM1, EDEM3, MAN1C1 |
| Tissue | NA |
| Tissue Specificity | Expressed ubiquitously in all tissues tested with slightly higher levels detected in small intestine and peripheral blood leukocytes and weakest levels in brain and skeletal muscle. {ECO:0000269|PubMed:15537790}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3746429 rs6060248 rs1052056 |
| Subcellular location [CC] | Endoplasmic reticulum lumen {ECO:0000269|PubMed:15537790}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |