| Gene Information | |
|---|---|
| Gene Name | M160 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1453 |
| Protein Names | Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9NR16 |
| Gene Card | CD163L1 |
| Uniprot ID | Q9NR16 |
| Pfam | PF00530 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Isoform 1 is highly expressed in the spleen, lymph nodes, thymus, and fetal liver and weakly expressed in bone marrow and no expression was found in peripheral blood leukocytes. Isoform 1 expression is restricted to the monocyte and macrophage cell lines. Isoform 2 is only expressed in spleen. {ECO:0000269|PubMed:11086079}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6K0O (X-ray 1.99A ) |
| DBSNP | rs6488268 rs4072797 rs4072796 rs36206713 rs35480970 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; [Isoform 2]: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.; [Isoform 3]: Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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