Gene Information
Gene NameMS4A3
OrganismHomo sapiens (Human)
Gene Length214
Protein NamesMembrane-spanning 4-domains subfamily A member 3 (CD20 antigen-like protein) (Hematopoietic-specific transmembrane protein 4) (HTm4)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000149516 )
3 ( ENSG00000284903 )
Evolutionary StageMammalia
AlphaFoldDBQ96HJ5
Gene CardMS4A3
Uniprot IDQ96HJ5
PfamPF04103
In ASDno
Allosteric Predictionno (-0.50953092)
Ortholog in AnimalsAlpaca_ MS4A3 ( ortholog_one2one )
Mouse_ Ms4a3 ( ortholog_one2one )
Rat_ Ms4a3 ( ortholog_one2one )
Rabbit_ MS4A3 ( ortholog_one2one )
OhnologsNA
ParalogsMS4A12, MS4A6E, MS4A6A, MS4A7, MS4A10, MS4A2, MS4A1, MS4A8, MS4A15, TMEM212, MS4A13, MS4A5, MS4A18, MS4A4E, MS4A4A, MS4A14
Tissuebone.marrow, lung, spleen
Tissue SpecificityExpressed specifically in hematopoietic cells and tissues.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Endomembrane system {ECO:0000250};
Multi-pass membrane protein {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Located in the perinuclear area.
Mouse PG classificationNA
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