Gene Information
Gene NameLZAP
OrganismHomo sapiens (Human)
Gene Length506
Protein NamesCDK5 regulatory subunit-associated protein 3 (CDK5 activator-binding protein C53) (LXXLL/leucine-zipper-containing ARF-binding protein) (Protein HSF-27)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ96JB5
Gene CardCDK5RAP3
Uniprot IDQ96JB5
PfamPF05600
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitously expressed (PubMed:12054757, PubMed:10721722). Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Isoform 3 is expressed in kidney, liver, skeletal muscle and placenta (PubMed:12737517). {ECO:0000269|PubMed:10721722, ECO:0000269|PubMed:12054757, ECO:0000269|PubMed:12737517}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs35054799 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:16173922}. Cytoplasm {ECO:0000269|PubMed:15790566, ECO:0000269|PubMed:16173922, ECO:0000269|PubMed:19223857}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:19223857}. Note=Colocalizes and associates with microtubules. {ECO:0000269|PubMed:23478299}.
Mouse PG classificationNA
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