| Gene Information | |
|---|---|
| Gene Name | LYZL6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 148 |
| Protein Names | Lysozyme-like protein 6 (EC 3.2.1.17) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000275722 ) 3 ( ENSG00000277042 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O75951 |
| Gene Card | LYZL6 |
| Uniprot ID | O75951 |
| Pfam | PF00062 |
| In ASD | no |
| Allosteric Prediction | no (-1.542348534) |
| Ortholog in Animals | Alpaca_ LYZL6 ( ortholog_one2one ) GuineaPig_ LYZL6 ( ortholog_one2one ) Macaque_ LYZL6 ( ortholog_one2one ) Mouse_ Lyzl6 ( ortholog_one2one ) Pig_ LYZL6 ( ortholog_one2one ) Rat_ Lyzl6 ( ortholog_one2one ) Rabbit_ LYZL6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LYZ, LYZL2, LYZL1, SPACA3, SPACA5B, SPACA5, LALBA, LYZL4 |
| Tissue | testis |
| Tissue Specificity | Expressed in testis, epididymis and spermatozoa (at protein level) (PubMed:16014814, PubMed:28182716). Expressed in late-stage spermatocytes and round spermatids (PubMed:28182716). {ECO:0000269|PubMed:16014814, ECO:0000269|PubMed:28182716}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9754 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:28182716}. Cell surface {ECO:0000269|PubMed:28182716}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q9DA11}. Note=Detected on the postacrosomal membrane of mature spermatozoa (PubMed:28182716). {ECO:0000269|PubMed:28182716}. |
| Mouse PG classification | NA |
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