| Gene Information | |
|---|---|
| Gene Name | SNX14 |
| Organism | Homo sapiens (Human) |
| Gene Length | 946 |
| Protein Names | Sorting nexin-14 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000135317 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9Y5W7 |
| Gene Card | SNX14 |
| Uniprot ID | Q9Y5W7 |
| Pfam | PF08628; PF00787; PF02194; PF00615 |
| In ASD | no |
| Allosteric Prediction | no (-1.43569941) |
| Ortholog in Animals | Alpaca_ SNX14 ( ortholog_one2one ) Dog_ SNX14 ( ortholog_one2one ) GuineaPig_ SNX14 ( ortholog_one2one ) Macaque_ SNX14 ( ortholog_one2one ) Mouse_ Snx14 ( ortholog_one2one ) Pig_ SNX14 ( ortholog_one2one ) Rat_ Snx14 ( ortholog_one2one ) Rabbit_ SNX14 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SNX25, SNX13, SNX19 |
| Tissue | NA |
| Tissue Specificity | Widely expressed both in fetal and adult tissues. {ECO:0000269|PubMed:25848753}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4BGJ (X-ray 2.55A ) 4PQO (X-ray 2.55A ) 4PQP (X-ray 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Lysosome membrane {ECO:0000269|PubMed:25848753}; Multi-pass membrane protein {ECO:0000305}. Late endosome membrane {ECO:0000269|PubMed:25848753}; Multi-pass membrane protein {ECO:0000305}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q8BHY8}. |
| Mouse PG classification | NA |
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