| Gene Information | |
|---|---|
| Gene Name | LYSAL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 616 |
| Protein Names | Ectonucleoside triphosphate diphosphohydrolase 4 (NTPDase 4) (EC 3.6.1.15) (EC 3.6.1.6) (Golgi UDPase) (Lysosomal apyrase-like protein of 70 kDa) (Uridine-diphosphatase) (UDPase) (EC 3.6.1.42) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9Y227 |
| Gene Card | ENTPD4 |
| Uniprot ID | Q9Y227 |
| Pfam | PF01150 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highest expression in testis and lowest in bladder. {ECO:0000269|PubMed:10393803, ECO:0000269|PubMed:9556635}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6WG5 (X-ray 2.60A ) |
| DBSNP | rs549468877 rs2272641 |
| Subcellular location [CC] | [Isoform 1]: Cytoplasmic vesicle, autophagosome membrane {ECO:0000269|PubMed:10393803}; Multi-pass membrane protein {ECO:0000305}. Lysosome membrane {ECO:0000269|PubMed:10393803}; Multi-pass membrane protein.; [Isoform 2]: Golgi apparatus membrane {ECO:0000269|PubMed:9556635}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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