| Gene Information | |
|---|---|
| Gene Name | LYRM4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 91 |
| Protein Names | LYR motif-containing protein 4 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 36 ( ENSG00000214113 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9HD34 |
| Gene Card | LYRM4 |
| Uniprot ID | Q9HD34 |
| Pfam | PF05347 |
| In ASD | no |
| Allosteric Prediction | no (-1.314279249) |
| Ortholog in Animals | Dog_ LYRM4 ( ortholog_one2one ) GuineaPig_ LYRM4 ( ortholog_one2one ) Mouse_ Lyrm4 ( ortholog_one2one ) Pig_ LYRM4 ( ortholog_one2one ) Rat_ Lyrm4 ( ortholog_one2one ) Rabbit_ LYRM4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SDHAF1 |
| Tissue | NA |
| Tissue Specificity | Reduced mRNA levels in Friedreich ataxia patients. {ECO:0000269|PubMed:17331979}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5USR (X-ray 3.09A ) 5WGB (X-ray 2.75A ) 5WKP (X-ray 3.15A ) 5WLW (X-ray 3.32A ) 6NZU (EM 3.20A ) 6ODD (X-ray 2.00A ) 6UXE (X-ray 1.57A ) 6W1D (X-ray 1.79A ) 6WI2 (X-ray 1.95A ) 6WIH (X-ray 1.90A ) 7RTK (X-ray 2.50A ) |
| DBSNP | rs2224391 rs587777218 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:17331979, ECO:0000269|PubMed:19454487}. Nucleus {ECO:0000269|PubMed:19454487}. |
| Mouse PG classification | NA |
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