| Gene Information | |
|---|---|
| Gene Name | LYPLA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 231 |
| Protein Names | Acyl-protein thioesterase 2 (APT-2) (EC 3.1.2.-) (Lysophospholipase II) (LPL-II) (LysoPLA II) (Palmitoyl-protein hydrolase) (EC 3.1.2.22) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000011009 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O95372 |
| Gene Card | LYPLA2 |
| Uniprot ID | O95372 |
| Pfam | PF02230 |
| In ASD | no |
| Allosteric Prediction | no (-1.099724185) |
| Ortholog in Animals | Alpaca_ LYPLA2 ( ortholog_one2one ) Dog_ PITHD1 ( ortholog_one2one ) GuineaPig_ LYPLA2 ( ortholog_one2one ) Macaque_ LYPLA2 ( ortholog_one2one ) Mouse_ Lypla2 ( ortholog_one2one ) Pig_ LYPLA2 ( ortholog_one2one ) Rat_ Lypla2 ( ortholog_one2one ) Rabbit_ LYPLA2 ( ortholog_one2one ) |
| Ohnologs | LYPLA1, LYPLA2P1 |
| Paralogs | LYPLA1, LYPLAL1 |
| Tissue | NA |
| Tissue Specificity | Expressed in various breast cancer cell lines. {ECO:0000269|PubMed:25301951}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 5SYN (X-ray 1.64A ) 6BJE (X-ray 2.70A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:25301951}. |
| Mouse PG classification | NA |
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