| Gene Information | |
|---|---|
| Gene Name | LXA4R |
| Organism | Homo sapiens (Human) |
| Gene Length | 351 |
| Protein Names | N-formyl peptide receptor 2 (FMLP-related receptor I) (FMLP-R-I) (Formyl peptide receptor-like 1) (HM63) (Lipoxin A4 receptor) (LXA4 receptor) (RFP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P25090 |
| Gene Card | FPR2 |
| Uniprot ID | P25090 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in lung, bone marrow, neutrophils, spleen and testis. {ECO:0000269|PubMed:15465011, ECO:0000269|PubMed:9151906}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6LW5 (X-ray 2.80A ) 6OMM (EM 3.17A ) 7T6S (EM 3.00A ) 7T6U (EM 2.90A ) 7T6V (EM 3.10A ) 7WVV (EM 2.90A ) 7WVW (EM 3.10A ) 7WVX (EM 2.80A ) 7WVY (EM 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:11689470, ECO:0000269|PubMed:15465011}; Multi-pass membrane protein. Note=Associates with Amyloid-beta protein 42, product of APP, at the cell surface and the complex is then rapidly internalized (PubMed:11689470). Also internalized in the presence of humanin (PubMed:15465011). {ECO:0000269|PubMed:11689470, ECO:0000269|PubMed:15465011}. |
| Mouse PG classification | NA |
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