| Gene Information | |
|---|---|
| Gene Name | LTRPC6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1104 |
| Protein Names | Transient receptor potential cation channel subfamily M member 8 (Long transient receptor potential channel 6) (LTrpC-6) (LTrpC6) (Transient receptor potential p8) (Trp-p8) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q7Z2W7 |
| Gene Card | TRPM8 |
| Uniprot ID | Q7Z2W7 |
| Pfam | PF00520; PF18139 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in prostate. Also expressed in prostate tumors and in non-prostatic primary tumors such as colon, lung, breast and skin tumors. {ECO:0000269|PubMed:11325849, ECO:0000269|PubMed:12858355, ECO:0000269|PubMed:16174775, ECO:0000269|PubMed:22128173}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs13004520 rs17868387 rs7593557 rs28902173 rs17862932 rs28902201 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. Membrane raft. Endoplasmic reticulum membrane. Note=Localizes to membrane rafts but is also located in the cell membrane outside of these regions where channel response to cold is enhanced compared to membrane rafts (By similarity). Located in the endoplasmic reticulum in prostate cancer cells. {ECO:0000250}. |
| Mouse PG classification | NA |
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