| Gene Information | |
|---|---|
| Gene Name | LTB4H |
| Organism | Homo sapiens (Human) |
| Gene Length | 520 |
| Protein Names | Cytochrome P450 4F3 (EC 1.14.14.1) (20-hydroxyeicosatetraenoic acid synthase) (20-HETE synthase) (CYPIVF3) (Cytochrome P450-LTB-omega) (Docosahexaenoic acid omega-hydroxylase CYP4F3) (EC 1.14.14.79) (Leukotriene-B(4) 20-monooxygenase 2) (Leukotriene-B(4) omega-hydroxylase 2) (EC 1.14.14.94) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q08477 |
| Gene Card | CYP4F3 |
| Uniprot ID | Q08477 |
| Pfam | PF00067 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | [Isoform CYP4F3A]: Selectively expressed in blood neutrophils and bone marrow cells. Coexpressed with CYP4F3B in prostate, ileum and trachea. {ECO:0000269|PubMed:11461919}.; [Isoform CYP4F3B]: Selectively expressed in liver and kidney. It is also the predominant CYP4F isoform in trachea and tissues of the gastrointestinal tract. {ECO:0000269|PubMed:11461919}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34923393 rs35888783 rs1805040 rs28371536 rs28371479 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000305|PubMed:10409674}; Single-pass membrane protein {ECO:0000255}. Microsome membrane {ECO:0000305|PubMed:10409674}; Single-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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