| Gene Information | |
|---|---|
| Gene Name | LTB4DH |
| Organism | Homo sapiens (Human) |
| Gene Length | 329 |
| Protein Names | Prostaglandin reductase 1 (PRG-1) (15-oxoprostaglandin 13-reductase) (EC 1.3.1.48) (Dithiolethione-inducible gene 1 protein) (D3T-inducible gene 1 protein) (DIG-1) (Leukotriene B4 12-hydroxydehydrogenase) (NAD(P)H-dependent alkenal/one oxidoreductase) (EC 1.3.1.74) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q14914 |
| Gene Card | PTGR1 |
| Uniprot ID | Q14914 |
| Pfam | PF16884; PF00107 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | High expression in the kidney, liver, and intestine but not in leukocytes. {ECO:0000269|PubMed:8576264}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1ZSV (X-ray 2.30A ) 2Y05 (X-ray 2.20A ) |
| DBSNP | rs1053959 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q29073}. |
| Mouse PG classification | NA |
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