| Gene Information | |
|---|---|
| Gene Name | CETP |
| Organism | Homo sapiens (Human) |
| Gene Length | 493 |
| Protein Names | Cholesteryl ester transfer protein (Lipid transfer protein I) |
| Target Name | cholesteryl ester transfer protein |
| Target Type | Clinical trial target |
| Gene Age | 680 ( ENSG00000087237 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P11597 |
| Gene Card | CETP |
| Uniprot ID | P11597 |
| Pfam | PF01273; PF02886 |
| In ASD | no |
| Allosteric Prediction | yes (0.553507864) |
| Ortholog in Animals | Alpaca_ CETP ( ortholog_one2one ) GuineaPig_ CETP ( ortholog_one2one ) Macaque_ CETP ( ortholog_one2one ) Rabbit_ CETP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BPI, PLTP, LBP, BPIFC, BPIFB2, BPIFB6, BPIFB4, BPIFB3, BPIFA2, BPIFA1, BPIFA3, BPIFB1 |
| Tissue | lymph.node, spleen, adipose.tissue |
| Tissue Specificity | Expressed by the liver and secreted in plasma. {ECO:0000269|PubMed:3281933}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2OBD (X-ray 2.10A ) 4EWS (X-ray 2.59A ) 4F2A (X-ray 3.11A ) |
| DBSNP | rs34065661 rs34716057 rs142459781 rs5881 rs34855278 rs5880 rs5882 rs2228667 rs2303790 rs1800777 rs5887 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:24293641, ECO:0000269|PubMed:3281933}. Note=Secreted in plasma. {ECO:0000269|PubMed:3281933}. |
| Mouse PG classification | NA |
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