Gene Information
Gene NameLST8
OrganismHomo sapiens (Human)
Gene Length326
Protein NamesTarget of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9BVC4
Gene CardMLST8
Uniprot IDQ9BVC4
PfamPF00400
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityBroadly expressed, with highest levels in skeletal muscle, heart and kidney. {ECO:0000269|PubMed:12408816}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4JSN  (X-ray  3.20A  4JSP  (X-ray  3.30A  4JSV  (X-ray  3.50A  4JSX  (X-ray  3.50A  4JT5  (X-ray  3.45A  4JT6  (X-ray  3.60A  5FLC  (EM  5.90A  5H64  (EM  4.40A  5WBU  (X-ray  3.42A  5WBY  (X-ray  3.10A  5ZCS  (EM  4.90A  6BCU  (EM  3.43A  6BCX  (EM  3.00A  6SB0  (EM  5.50A  6SB2  (EM  6.20A  6ZWM  (EM  3.20A  6ZWO  (EM  3.00A  7OWG  (EM  4.70A  7PE7  (EM  3.41A  7PE8  (EM  3.20A  7PE9  (EM  3.70A  7PEA  (EM  4.07A  7PEB  (EM  3.67A  7PEC  (EM  4.24A 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000250|UniProtKB:Q9Z2K5}.
Mouse PG classificationNA
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