Gene Information
Gene NameSMVT
OrganismHomo sapiens (Human)
Gene Length635
Protein NamesSodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter) (Solute carrier family 5 member 6)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9Y289
Gene CardSLC5A6
Uniprot IDQ9Y289
PfamPF00474
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in microvessels of the brain (at protein level) (PubMed:25809983). Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas (PubMed:10329687). {ECO:0000269|PubMed:10329687, ECO:0000269|PubMed:25809983}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs994218778  rs370950187  rs1395  rs1064845 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:25809983, ECO:0000269|PubMed:27904971};
Multi-pass membrane protein {ECO:0000255}.;
Cell membrane {ECO:0000269|PubMed:28052864};
Multi-pass membrane protein {ECO:0000255}. Note=(Microbial infection) Exposure to E.coli lipopolysaccharides leeds to reduced cell membrane localization. {ECO:0000269|PubMed:28052864}.
Mouse PG classificationNA
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