Gene Information
Gene NameLSG1
OrganismHomo sapiens (Human)
Gene Length658
Protein NamesLarge subunit GTPase 1 homolog (hLsg1) (EC 3.6.1.-)
Target NameNA
Target TypeNA
Gene Age>4290 ( ENSG00000041802 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ9H089
Gene CardLSG1
Uniprot IDQ9H089
PfamPF01926
In ASDno
Allosteric Predictionno (-1.54300676)
Ortholog in AnimalsAlpaca_ LSG1 ( ortholog_one2one )
Dog_ LSG1 ( ortholog_one2one )
Macaque_ LSG1 ( ortholog_one2one )
Mouse_ Lsg1 ( ortholog_one2one )
Pig_ LSG1 ( ortholog_one2one )
Rat_ Lsg1 ( ortholog_one2one )
Rabbit_ LSG1 ( ortholog_one2one )
OhnologsNA
ParalogsNOA1, GNL2, GNL1, MTG1, GNL3, GNL3L
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.049505(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 6LSR  (EM  3.13A 
DBSNP rs34423045  rs1675953 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:16209721}. Endoplasmic reticulum {ECO:0000269|PubMed:16209721}. Nucleus, Cajal body {ECO:0000269|PubMed:16209721}. Note=Shuttles between the Cajal bodies in the nucleus and the endoplasmic reticulum.
Mouse PG classificationNA
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