| Gene Information | |
|---|---|
| Gene Name | LRTOMT |
| Organism | Homo sapiens (Human) |
| Gene Length | 291 |
| Protein Names | Transmembrane O-methyltransferase (EC 2.1.1.6) (Catechol O-methyltransferase 2) (Protein LRTOMT2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000284922 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8WZ04 |
| Gene Card | TOMT |
| Uniprot ID | Q8WZ04 |
| Pfam | PF01596 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs891068154 rs1372399805 rs137853185 rs137853186 rs137853187 rs758115449 rs61741195 |
| Subcellular location [CC] | [Isoform 1]: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.; [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:28504928}. Endoplasmic reticulum {ECO:0000250|UniProtKB:A1Y9I9}. Note=Localized to the cell body of the cochlear hair cells, but is not present in the stereocilia (PubMed:28504928). Present but not restricted to the apical cistern, Hensen's body and the subsurface cistern (By similarity). {ECO:0000250|UniProtKB:A1Y9I9, ECO:0000269|PubMed:28504928}. |
| Mouse PG classification | NA |
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