| Gene Information | |
|---|---|
| Gene Name | LRRTM2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 516 |
| Protein Names | Leucine-rich repeat transmembrane neuronal protein 2 (Leucine-rich repeat neuronal 2 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000146006 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O43300 |
| Gene Card | LRRTM2 |
| Uniprot ID | O43300 |
| Pfam | PF13855 |
| In ASD | no |
| Allosteric Prediction | no (-0.548918356) |
| Ortholog in Animals | Alpaca_ LRRTM2 ( ortholog_one2one ) Dog_ LRRTM2 ( ortholog_one2one ) GuineaPig_ LRRTM2 ( ortholog_one2one ) Macaque_ LRRTM2 ( ortholog_one2one ) Mouse_ Lrrtm2 ( ortholog_one2one ) Pig_ LRRTM2 ( ortholog_one2one ) Rat_ Lrrtm2 ( ortholog_one2one ) Rabbit_ LRRTM2 ( ortholog_one2one ) |
| Ohnologs | LINGO1, LRG1, LRRTM4, CPN2 |
| Paralogs | LRG1, CPN2, LRRC52, LRIT3, LRRC24, ELFN2, LRIG3, LGR6, LGR5, CHAD, CHADL, LRIT1, TRIL, ELFN1, LGR4, LGI2, LGI1, LRIG2, LRRC26, LRIG1, LGI3, LGI4 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Expressed in neuronal tissues. {ECO:0000269|PubMed:12676565}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5Z8X (X-ray 3.15A ) 5Z8Y (X-ray 3.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. Postsynaptic cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Localized to excitatory synapses. {ECO:0000250}. |
| Mouse PG classification | NA |
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