| Gene Information | |
|---|---|
| Gene Name | LRRTM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 522 |
| Protein Names | Leucine-rich repeat transmembrane neuronal protein 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000162951 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q86UE6 |
| Gene Card | LRRTM1 |
| Uniprot ID | Q86UE6 |
| Pfam | PF13855 |
| In ASD | no |
| Allosteric Prediction | no (-0.292679458) |
| Ortholog in Animals | Alpaca_ LRRTM1 ( ortholog_one2one ) Dog_ LRRTM1 ( ortholog_one2one ) GuineaPig_ LRRTM1 ( ortholog_one2one ) Macaque_ LRRTM1 ( ortholog_one2one ) Mouse_ Lrrtm1 ( ortholog_one2one ) Pig_ LRRTM1 ( ortholog_one2one ) Rat_ LRRTM1 ( ortholog_one2one ) Rabbit_ LRRTM1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LRTM1, LRRTM3, BGN, LRRC19, RTN4RL2, LRRC4B, NYX, PODN, LRRC15, FLRT2, FLRT1, LRRTM4, LRRC66, RTN4RL1, LRRC4, ASPN, PODNL1, FLRT3, DCN, GP1BA, RTN4R, LRRC4C |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in forebrain regions including thalamus and cerebral cortex. {ECO:0000269|PubMed:12676565, ECO:0000269|PubMed:17667961}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6733871 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Postsynaptic cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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