| Gene Information | |
|---|---|
| Gene Name | LRRK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2015 |
| Protein Names | Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000154237 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q38SD2 |
| Gene Card | LRRK1 |
| Uniprot ID | Q38SD2 |
| Pfam | PF12796; PF16095; PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.195349868) |
| Ortholog in Animals | Alpaca_ LRRK1 ( ortholog_one2one ) Dog_ LRRK1 ( ortholog_one2one ) GuineaPig_ LRRK1 ( ortholog_one2one ) Macaque_ LRRK1 ( ortholog_one2one ) Mouse_ Lrrk1 ( ortholog_one2one ) Pig_ LRRK1 ( ortholog_one2one ) Rat_ Lrrk1 ( ortholog_one2one ) Rabbit_ LRRK1 ( ortholog_one2one ) |
| Ohnologs | LRRK2 |
| Paralogs | LRRC8B, LRRIQ4, LRRC18, LRCH4, LRRC58, LRRD1, PHLPP1, ERBIN, LRRC8C, LRCH2, MFHAS1, SCRIB, LRRC1, LRRC2, PIDD1, LRRC30, LRRC27, LRRC8E, LRRC7, LRCH1, LRRC8A, LRRC8D, LRRC10, LRRC10B, LRRC40, SHOC2, PHLPP2, LRCH3, LRRC69, LRRC39, LRRC28 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16243488}. |
| Mouse PG classification | NA |
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