| Gene Information | |
|---|---|
| Gene Name | CST5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 142 |
| Protein Names | Cystatin-D (Cystatin-5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000170367 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P28325 |
| Gene Card | CST5 |
| Uniprot ID | P28325 |
| Pfam | PF00031 |
| In ASD | no |
| Allosteric Prediction | no (-0.999007978) |
| Ortholog in Animals | Alpaca_ CST5 ( ortholog_one2one ) Macaque_ CST5 ( ortholog_one2one ) |
| Ohnologs | CST6 |
| Paralogs | CST3, CST2, CST4, CST1, CST8, CST9, CST9L, CSTL1, CST11, CST6, CST7 |
| Tissue | salivary.gland, parotid.gland |
| Tissue Specificity | Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in parotid gland but not in seminal vesicle, prostate, epididymis, testis, ovary, placenta, thyroid, gastric corpus, small intestine, liver, or gall bladder tissue. {ECO:0000269|PubMed:20189825}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1RN7 (X-ray 2.50A ) 1ROA (X-ray 1.80A ) |
| DBSNP | rs1799841 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:20189825}. |
| Mouse PG classification | NA |
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