| Gene Information | |
|---|---|
| Gene Name | NARS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 477 |
| Protein Names | Probable asparagine--tRNA ligase, mitochondrial (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS) |
| Target Name | probable asparagine--trna ligase, mitochondrial |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000137513 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q96I59 |
| Gene Card | NARS2 |
| Uniprot ID | Q96I59 |
| Pfam | PF00152; PF01336 |
| In ASD | no |
| Allosteric Prediction | no (-0.393857693) |
| Ortholog in Animals | Alpaca_ NARS2 ( ortholog_one2one ) Dog_ GAB2 ( ortholog_one2one ) GuineaPig_ NARS2 ( ortholog_one2one ) Macaque_ NARS2 ( ortholog_one2one ) Mouse_ Nars2 ( ortholog_one2one ) Pig_ NARS2 ( ortholog_one2one ) Rat_ Nars2 ( ortholog_one2one ) Rabbit_ NARS2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DARS2, NARS1, KARS1, DARS1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10501429 rs756725793 rs730882155 rs1565216037 |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000250}. Mitochondrion {ECO:0000269|PubMed:25807530, ECO:0000269|PubMed:35558980}. |
| Mouse PG classification | NA |
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