| Gene Information | |
|---|---|
| Gene Name | LRRC49 |
| Organism | Homo sapiens (Human) |
| Gene Length | 686 |
| Protein Names | Leucine-rich repeat-containing protein 49 (Centriolar satellite-associated tubulin polyglutamylase complex regulator 2) (Tubulin polyglutamylase complex subunit 4) (PGs4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000137821 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8IUZ0 |
| Gene Card | LRRC49 |
| Uniprot ID | Q8IUZ0 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.94273772) |
| Ortholog in Animals | Alpaca_ LRRC49 ( ortholog_one2one ) Dog_ LRRC49 ( ortholog_one2one ) GuineaPig_ LRRC49 ( ortholog_one2one ) Macaque_ LRRC49 ( ortholog_one2one ) Mouse_ Lrrc49 ( ortholog_one2one ) Pig_ LRRC49 ( ortholog_one2one ) Rat_ Lrrc49 ( ortholog_one2one ) Rabbit_ LRRC49 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LRRC43, DNAAF11, DRC3, LRRCC1, LRRC9, LRRC46, DNAAF1, CEP97, LRRC23, PPP1R42, LRRC61, LRRIQ3, LRGUK |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.156200(Rat);0.160000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:34782749}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:34782749}. Note=Associated with microtubules. {ECO:0000269|PubMed:34782749}. |
| Mouse PG classification | NA |
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