| Gene Information | |
|---|---|
| Gene Name | TNNC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 161 |
| Protein Names | Troponin C, slow skeletal and cardiac muscles (TN-C) |
| Target Name | troponin c |
| Target Type | Successful target |
| Gene Age | 950 ( ENSG00000114854 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P63316 |
| Gene Card | TNNC1 |
| Uniprot ID | P63316 |
| Pfam | PF13499; PF13833 |
| In ASD | yes |
| Allosteric Prediction | yes (0.256566351) |
| Ortholog in Animals | Alpaca_ TNNC1 ( ortholog_one2one ) Dog_ TNNC1 ( ortholog_one2one ) GuineaPig_ TNNC1 ( ortholog_one2one ) Macaque_ TNNC1 ( ortholog_one2one ) Mouse_ Tnnc1 ( ortholog_one2one ) Pig_ TNNC1 ( ortholog_one2one ) Rat_ Tnnc1 ( ortholog_one2one ) Rabbit_ TNNC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TNNC2 |
| Tissue | skeletal.muscle, artery, heart, left.ventricle, pulmonary.valve, tongue |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.059533(Rat);0.094444(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1AP4 (NMR - ) 1IH0 (NMR - ) 1J1D (X-ray 2.61A ) 1J1E (X-ray 3.30A ) 1LXF (NMR - ) 1MXL (NMR - ) 1OZS (NMR - ) 1SPY (NMR - ) 1WRK (X-ray 2.15A ) 1WRL (X-ray 2.60A ) 2JT0 (NMR - ) 2JT3 (NMR - ) 2JT8 (NMR - ) 2JTZ (NMR - ) 2JXL (NMR - ) 2KDH (NMR - ) 2KFX (NMR - ) 2KGB (NMR - ) 2KRD (NMR - ) 2L1R (NMR - ) 2L98 (NMR - ) 2MKP (NMR - ) 2MLE (NMR - ) 2MLF (NMR - ) 2MZP (NMR - ) 2N79 (NMR - ) 2N7L (NMR - ) 3RV5 (X-ray 2.20A ) 3SD6 (X-ray 1.37A ) 3SWB (X-ray 1.67A ) 4GJE (X-ray 1.60A ) 4GJF (X-ray 1.90A ) 4GJG (X-ray 2.00A ) 4Y99 (X-ray 2.00A ) 5VLN (NMR - ) 5W88 (NMR - ) 5WCL (NMR - ) 6KN7 (EM 6.60A ) 6KN8 (EM 4.80A ) 6MV3 (NMR - ) 7JGI (NMR - ) 7SC2 (X-ray 1.81A ) 7SC3 (X-ray 2.23A ) 7SUP (NMR - ) 7SVC (NMR - ) 7SWG (NMR - ) 7SWI (NMR - ) 7SXC (NMR - ) 7SXD (NMR - ) 7UH9 (NMR - ) 7UHA (NMR - ) |
| DBSNP | rs267607125 rs267607123 rs267607126 rs397516847 rs267607124 rs104893823 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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