| Gene Information | |
|---|---|
| Gene Name | LRRC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 257 |
| Protein Names | Leucine-rich repeat-containing protein 3 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000160233 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BY71 |
| Gene Card | LRRC3 |
| Uniprot ID | Q9BY71 |
| Pfam | PF00560; PF13855; PF01462 |
| In ASD | no |
| Allosteric Prediction | no (-1.307306235) |
| Ortholog in Animals | Alpaca_ LRRC3 ( ortholog_one2one ) GuineaPig_ LRRC3 ( ortholog_one2one ) Macaque_ LRRC3 ( ortholog_one2one ) Mouse_ Lrrc3 ( ortholog_one2one ) Pig_ LRRC3 ( ortholog_one2one ) Rat_ Lrrc3 ( ortholog_one2one ) Rabbit_ LRRC3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LRRC3C, CD180, RXFP1, TLR8, NRROS, TLR5, TSKU, TLR7, TLR10, RXFP2, TLR6, LRRC3B, IGFALS, TLR3, TLR2, TLR4, LRRC17, LRRC32, LRRC53, VASN, TLR1, LRIT2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed; detected in testis, lung, small intestine, breast, brain, heart, bone marrow, placenta, colon, fetal brain, liver, fetal liver, thymus, salivary gland, spinal cord, spleen, trachea and adrenal gland. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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