| Gene Information | |
|---|---|
| Gene Name | LRR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 414 |
| Protein Names | Leucine-rich repeat protein 1 (4-1BB-mediated-signaling molecule) (4-1BBlrr) (LRR-repeat protein 1) (LRR-1) (Peptidylprolyl isomerase-like 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000165501 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96L50 |
| Gene Card | LRR1 |
| Uniprot ID | Q96L50 |
| Pfam | PF12799 |
| In ASD | no |
| Allosteric Prediction | no (-0.799311759) |
| Ortholog in Animals | Alpaca_ LRR1 ( ortholog_one2one ) Dog_ LRR1 ( ortholog_one2one ) GuineaPig_ LRR1 ( ortholog_one2one ) Macaque_ LRR1 ( ortholog_one2one ) Mouse_ Lrr1 ( ortholog_one2one ) Pig_ LRR1 ( ortholog_one2one ) Rat_ Lrr1 ( ortholog_one2one ) Rabbit_ LRR1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Maximal expression was seen in the heart and skeletal muscle and minimal expression seen in the kidney. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.06(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7PLO (EM 2.80A ) |
| DBSNP | rs17121605 rs7148147 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:34700328}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |