Gene Information
Gene NameLRP2BP
OrganismHomo sapiens (Human)
Gene Length347
Protein NamesLRP2-binding protein (Megalin-binding protein) (MegBP)
Target NameNA
Target TypeNA
Gene Age1064 ( ENSG00000109771 )
Evolutionary StageOpisthokonta
AlphaFoldDBQ9P2M1
Gene CardLRP2BP
Uniprot IDQ9P2M1
PfamPF08238
In ASDno
Allosteric Predictionno (-1.471731579)
Ortholog in AnimalsAlpaca_ LRP2BP ( ortholog_one2one )
Dog_ LRP2BP ( ortholog_one2one )
GuineaPig_ LRP2BP ( ortholog_one2one )
Macaque_ LRP2BP ( ortholog_one2one )
Mouse_ Lrp2bp ( ortholog_one2one )
Pig_ LRP2BP ( ortholog_one2one )
Rat_ Lrp2bp ( ortholog_one2one )
Rabbit_ LRP2BP ( ortholog_one2one )
OhnologsNA
ParalogsSEL1L2, SEL1L3, SEL1L, DELE1
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:12508107}. Note=Detected in a vesicular staining pattern close to the plasma membrane and throughout the cytoplasm.
Mouse PG classificationNA
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