Gene Information
Gene NameLRIT1
OrganismHomo sapiens (Human)
Gene Length623
Protein NamesLeucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 (Leucine-rich repeat-containing protein 21) (Photoreceptor-associated LRR superfamily protein) (Retina-specific protein PAL)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000148602 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9P2V4
Gene CardLRIT1
Uniprot IDQ9P2V4
PfamPF00041; PF07679; PF13855
In ASDno
Allosteric Predictionno (-1.581213418)
Ortholog in AnimalsAlpaca_ LRIT1 ( ortholog_one2one )
Dog_ LRIT1 ( ortholog_one2one )
GuineaPig_ LRIT1 ( ortholog_one2one )
Macaque_ LRIT1 ( ortholog_one2one )
Mouse_ Lrit1 ( ortholog_one2one )
Pig_ LRIT1 ( ortholog_one2one )
Rat_ Lrit1 ( ortholog_one2one )
Rabbit_ LRIT1 ( ortholog_one2one )
OhnologsLRIT3
ParalogsLRG1, CPN2, LRRTM2, LRRC52, LRIT3, LRRC24, ELFN2, LRIG3, LGR6, LGR5, CHAD, CHADL, TRIL, ELFN1, LGR4, LGI2, LGI1, LRIG2, LRRC26, LRIG1, LGI3, LGI4
Tissuepineal.gland
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs11200933  rs7090059  rs12262099  rs3814211 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9JMH2};
Single-pass type I membrane protein {ECO:0000250}.
Mouse PG classificationNA
click here to return to the previous page