| Gene Information | |
|---|---|
| Gene Name | LRFN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 771 |
| Protein Names | Leucine-rich repeat and fibronectin type III domain-containing protein 1 (Synaptic adhesion-like molecule 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000128011 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9P244 |
| Gene Card | LRFN1 |
| Uniprot ID | Q9P244 |
| Pfam | PF00041; PF07679; PF13855 |
| In ASD | no |
| Allosteric Prediction | no (-0.477288546) |
| Ortholog in Animals | Alpaca_ LRFN1 ( ortholog_one2one ) Dog_ LRFN1 ( ortholog_one2one ) GuineaPig_ LRFN1 ( ortholog_one2one ) Macaque_ LRFN1 ( ortholog_one2one ) Mouse_ Lrfn1 ( ortholog_one2one ) Pig_ LRFN1 ( ortholog_one2one ) Rat_ Lrfn1 ( ortholog_one2one ) Rabbit_ LRFN1 ( ortholog_one2one ) |
| Ohnologs | LRRC4B, LRFN5, LRFN4 |
| Paralogs | TLR9, LRRC70, LRFN2, LRFN5, SLITRK3, LRFN4, GP5, SLITRK2, LINGO1, TPBGL, SLITRK6, LRRN1, SLITRK1, LRTM2, SLIT3, LRRN2, LRRN3, SLIT2, LRRC38, SLITRK4, LINGO2, SLIT1, SLITRK5, LRRC55, LRFN3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Synapse {ECO:0000250}. Postsynaptic density membrane {ECO:0000250}. Note=Detected in excitatory, but not inhibitory, synaptic plasma membrane. {ECO:0000250}. |
| Mouse PG classification | NA |
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