| Gene Information | |
|---|---|
| Gene Name | LRDD |
| Organism | Homo sapiens (Human) |
| Gene Length | 910 |
| Protein Names | p53-induced death domain-containing protein 1 (EC 3.4.21.-) (Leucine-rich repeat and death domain-containing protein) [Cleaved into: PIDD-N; PIDD-C; PIDD-CC] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9HB75 |
| Gene Card | PIDD1 |
| Uniprot ID | Q9HB75 |
| Pfam | PF00531; PF13855; PF10461; PF00791 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:10825539}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2OF5 (X-ray 3.20A ) |
| DBSNP | rs10902221 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16360037, ECO:0000269|PubMed:17159900}. Nucleus {ECO:0000269|PubMed:16360037, ECO:0000269|PubMed:17159900}. Note=Enriched in the nucleus upon DNA damage. {ECO:0000269|PubMed:17159900}. |
| Mouse PG classification | NA |
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