| Gene Information | |
|---|---|
| Gene Name | CENPL |
| Organism | Homo sapiens (Human) |
| Gene Length | 344 |
| Protein Names | Centromere protein L (CENP-L) (Interphase centromere complex protein 33) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000120334 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8N0S6 |
| Gene Card | CENPL |
| Uniprot ID | Q8N0S6 |
| Pfam | PF13092 |
| In ASD | no |
| Allosteric Prediction | no (-0.251089775) |
| Ortholog in Animals | Alpaca_ CENPL ( ortholog_one2one ) Dog_ CENPL ( ortholog_one2one ) GuineaPig_ CENPL ( ortholog_one2one ) Macaque_ CENPL ( ortholog_one2one ) Mouse_ Cenpl ( ortholog_one2one ) Pig_ CENPL ( ortholog_one2one ) Rat_ Cenpl ( ortholog_one2one ) Rabbit_ CENPL ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7PKN (EM 3.20A ) 7QOO (EM 4.60A ) 7R5S (EM 2.83A ) 7R5V (EM 4.55A ) 7YWX (EM 12.00A ) 7YYH (EM 8.90A ) |
| DBSNP | rs12086855 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16716197}. Chromosome, centromere {ECO:0000269|PubMed:16716197}. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex. |
| Mouse PG classification | NA |
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