| Gene Information | |
|---|---|
| Gene Name | LPTL |
| Organism | Homo sapiens (Human) |
| Gene Length | 328 |
| Protein Names | PIN2/TERF1-interacting telomerase inhibitor 1 (Liver-related putative tumor suppressor) (Pin2-interacting protein X1) (Protein 67-11-3) (TRF1-interacting protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96BK5 |
| Gene Card | PINX1 |
| Uniprot ID | Q96BK5 |
| Pfam | PF01585 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous; expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35530857 rs17855458 rs17711777 rs1078543 rs34656824 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:27847364}. Nucleus, nucleolus. Chromosome, telomere. Chromosome, centromere, kinetochore. Note=Localizes in nucleoli, at telomere speckles and to the outer plate of kinetochores. Localization to the kinetochore is mediated by its central region and depends on NDC80 and CENPE. |
| Mouse PG classification | NA |
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