| Gene Information | |
|---|---|
| Gene Name | HEBP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 205 |
| Protein Names | Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000051620 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y5Z4 |
| Gene Card | HEBP2 |
| Uniprot ID | Q9Y5Z4 |
| Pfam | PF04832 |
| In ASD | no |
| Allosteric Prediction | yes (0.251491585) |
| Ortholog in Animals | Alpaca_ HEBP2 ( ortholog_one2one ) Dog_ HEBP2 ( ortholog_one2one ) GuineaPig_ HEBP2 ( ortholog_one2one ) Macaque_ HEBP2 ( ortholog_one2one ) Mouse_ Hebp2 ( ortholog_one2one ) Rat_ Hebp2 ( ortholog_one2one ) Rabbit_ HEBP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HEBP1 |
| Tissue | breast |
| Tissue Specificity | Detected in placenta. {ECO:0000269|PubMed:2018407}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3R85 (X-ray 1.95A ) 3R8J (X-ray 1.60A ) 3R8K (X-ray 2.85A ) 4AYZ (X-ray 3.50A ) 4B0Y (X-ray 3.50A ) 5GQQ (X-ray 2.20A ) |
| DBSNP | rs3734303 rs14812 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17098234}. Mitochondrion {ECO:0000269|PubMed:17098234}. Note=Mainly localized to the cytoplasm with a much lower abundance in the mitochondrion. {ECO:0000269|PubMed:17098234}. |
| Mouse PG classification | NA |
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