| Gene Information | |
|---|---|
| Gene Name | LPP |
| Organism | Homo sapiens (Human) |
| Gene Length | 612 |
| Protein Names | Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000145012 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q93052 |
| Gene Card | LPP |
| Uniprot ID | Q93052 |
| Pfam | PF00412 |
| In ASD | no |
| Allosteric Prediction | no (-0.937532485) |
| Ortholog in Animals | Alpaca_ LPP ( ortholog_one2one ) Dog_ LPP ( ortholog_one2one ) GuineaPig_ LPP ( ortholog_one2one ) Macaque_ LPP ( ortholog_one2one ) Mouse_ Lpp ( ortholog_one2one ) Pig_ LPP ( ortholog_one2one ) Rat_ Lpp ( ortholog_one2one ) Rabbit_ LPP ( ortholog_one2one ) |
| Ohnologs | ZYX, LIMD1 |
| Paralogs | FBLIM1 |
| Tissue | NA |
| Tissue Specificity | Expressed in a wide variety of tissues but no or very low expression in brain and peripheral leukocytes. {ECO:0000269|PubMed:10637295, ECO:0000269|PubMed:8812423}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35417432 rs35940579 rs7645635 |
| Subcellular location [CC] | Nucleus. Cytoplasm. Cell junction. Cell membrane. Note=Found in the nucleus, in the cytoplasm and at cell adhesion sites. Shuttles between the cytoplasm and the nucleus. It has been found in sites of cell adhesion such as cell-to-cell contact and focal adhesion which are membrane attachment sites of cells to the extracellular matrix. Mainly nuclear when fused with HMGA2/HMGIC and KMT2A/MLL1. |
| Mouse PG classification | NA |
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