| Gene Information | |
|---|---|
| Gene Name | LPL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 230 |
| Protein Names | Acyl-protein thioesterase 1 (APT-1) (hAPT1) (EC 3.1.2.-) (Lysophospholipase 1) (Lysophospholipase I) (LPL-I) (LysoPLA I) (Palmitoyl-protein hydrolase) (EC 3.1.2.22) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O75608 |
| Gene Card | LYPLA1 |
| Uniprot ID | O75608 |
| Pfam | PF02230 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Platelets. {ECO:0000269|PubMed:21393252}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1FJ2 (X-ray 1.50A ) 5SYM (X-ray 1.55A ) 6QGN (X-ray 2.10A ) 6QGO (X-ray 2.60A ) 6QGQ (X-ray 2.60A ) 6QGS (X-ray 2.75A ) |
| DBSNP | rs11549448 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19439193}. Cell membrane {ECO:0000269|PubMed:19439193}. Nucleus membrane {ECO:0000269|PubMed:19439193}. Endoplasmic reticulum {ECO:0000269|PubMed:19439193}. Note=Shows predominantly a cytoplasmic localization with a weak expression in the cell membrane, nuclear membrane and endoplasmic reticulum. {ECO:0000269|PubMed:19439193}. |
| Mouse PG classification | NA |
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