| Gene Information | |
|---|---|
| Gene Name | STX4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 297 |
| Protein Names | Syntaxin-4 (Renal carcinoma antigen NY-REN-31) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000103496 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q12846 |
| Gene Card | STX4 |
| Uniprot ID | Q12846 |
| Pfam | PF05739; PF00804 |
| In ASD | no |
| Allosteric Prediction | no (-0.119575082) |
| Ortholog in Animals | Alpaca_ STX4 ( ortholog_one2one ) Dog_ STX4 ( ortholog_one2one ) GuineaPig_ STX4 ( ortholog_one2one ) Macaque_ STX4 ( ortholog_one2one ) Mouse_ Stx4a ( ortholog_one2one ) Pig_ STX4 ( ortholog_one2one ) Rat_ Stx4 ( ortholog_one2one ) Rabbit_ STX4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | STX19, STX11, STX16, STX12, STX5, STX17, STX7, TSNARE1, STX2, STX3, STX1A, STX1B |
| Tissue | NA |
| Tissue Specificity | Expressed in neutrophils and neutrophil-differentiated HL-60 cells. Expression in neutrophils increases with differentiation. {ECO:0000269|PubMed:10080545}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.098730(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q08850}; Single-pass type IV membrane protein {ECO:0000305}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q08850}. Note=Localizes to neurite tips in neuronal cells. {ECO:0000250|UniProtKB:Q08850}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |