| Gene Information | |
|---|---|
| Gene Name | LPIN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 896 |
| Protein Names | Phosphatidate phosphatase LPIN2 (EC 3.1.3.4) (Lipin-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000101577 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q92539 |
| Gene Card | LPIN2 |
| Uniprot ID | Q92539 |
| Pfam | PF16876; PF04571; PF08235 |
| In ASD | no |
| Allosteric Prediction | no (-0.529243589) |
| Ortholog in Animals | Alpaca_ LPIN2 ( ortholog_one2one ) Dog_ LPIN2 ( ortholog_one2one ) GuineaPig_ LPIN2 ( ortholog_one2one ) Macaque_ LPIN2 ( ortholog_one2one ) Mouse_ Lpin2 ( ortholog_one2one ) Pig_ LPIN2 ( ortholog_one2one ) Rat_ Lpin2 ( ortholog_one2one ) Rabbit_ LPIN2 ( ortholog_one2one ) |
| Ohnologs | LPIN3, LPIN1 |
| Paralogs | AP5Z1, LPIN3, LPIN1 |
| Tissue | NA |
| Tissue Specificity | Expressed in liver, lung, kidney, placenta, spleen, thymus, lymph node, prostate, testes, small intestine, and colon. {ECO:0000269|PubMed:15994876, ECO:0000269|PubMed:17158099}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs80338807 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}. Note=Translocates to endoplasmic reticulum membrane with increasing levels of oleate. {ECO:0000250}. |
| Mouse PG classification | LPG |
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