| Gene Information | |
|---|---|
| Gene Name | LPCAT4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 524 |
| Protein Names | Lysophospholipid acyltransferase LPCAT4 (1-acylglycerol-3-phosphate O-acyltransferase 7) (1-AGP acyltransferase 7) (1-AGPAT 7) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (1-alkenylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.121) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acyltransferase-like 3) (Lysophosphatidylcholine acyltransferase 4) (Lysophosphatidylethanolamine acyltransferase 2) (EC 2.3.1.n7) (Plasmalogen synthase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000176454 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q643R3 |
| Gene Card | LPCAT4 |
| Uniprot ID | Q643R3 |
| Pfam | PF01553 |
| In ASD | no |
| Allosteric Prediction | no (-0.918690451) |
| Ortholog in Animals | Alpaca_ LPCAT4 ( ortholog_one2one ) GuineaPig_ LPCAT4 ( ortholog_one2one ) Macaque_ LPCAT4 ( ortholog_one2one ) Mouse_ Lpcat4 ( ortholog_one2one ) Pig_ LPCAT4 ( ortholog_one2one ) Rat_ Lpcat4 ( ortholog_one2one ) Rabbit_ LPCAT4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LPCAT2, LPCAT1, GPAT4, GPAT3 |
| Tissue | NA |
| Tissue Specificity | Widely expressed with predominant level in brain. {ECO:0000269|PubMed:16243729, ECO:0000269|PubMed:18458083}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:16243729, ECO:0000269|PubMed:18458083}; Multi-pass membrane protein {ECO:0000269|PubMed:16243729, ECO:0000269|PubMed:18458083}. |
| Mouse PG classification | NA |
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