| Gene Information | |
|---|---|
| Gene Name | LPCAT4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 520 |
| Protein Names | Lysophospholipid acyltransferase 2 (LPLAT 2) (EC 2.3.1.-) (1-acylglycerophosphate O-acyltransferase MBOAT2) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase MBOAT2) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine MBOAT2 O-acyltransferase) (EC 2.3.1.n7) (Lysophosphatidic acid acyltransferase) (LPAAT) (Lyso-PA acyltransferase) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 4) (Lyso-PC acyltransferase 4) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 2) (O-acyltransferase domain-containing protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000176454 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6ZWT7 |
| Gene Card | MBOAT2 |
| Uniprot ID | Q6ZWT7 |
| Pfam | PF03062 |
| In ASD | no |
| Allosteric Prediction | no (-0.918690451) |
| Ortholog in Animals | Alpaca_ LPCAT4 ( ortholog_one2one ) GuineaPig_ LPCAT4 ( ortholog_one2one ) Macaque_ LPCAT4 ( ortholog_one2one ) Mouse_ Lpcat4 ( ortholog_one2one ) Pig_ LPCAT4 ( ortholog_one2one ) Rat_ Lpcat4 ( ortholog_one2one ) Rabbit_ LPCAT4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LPCAT2, LPCAT1, GPAT4, GPAT3 |
| Tissue | NA |
| Tissue Specificity | Expressed in neutrophils. {ECO:0000269|PubMed:18772128}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16866827 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8R3I2}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |