Gene Information
Gene NameLPCAT2
OrganismHomo sapiens (Human)
Gene Length544
Protein NamesLysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2) (LPCAT-2) (LysoPC acyltransferase 2) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase 11) (1-AGP acyltransferase 11) (1-AGPAT 11) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkenylglycerophosphocholine O-acyltransferase) (EC 2.3.1.25) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000087253 )
Evolutionary StageEukaryota
AlphaFoldDBQ7L5N7
Gene CardLPCAT2
Uniprot IDQ7L5N7
PfamPF01553; PF00036; PF13202
In ASDno
Allosteric Predictionno (-0.511480035)
Ortholog in AnimalsAlpaca_ LPCAT2 ( ortholog_one2one )
Dog_ LPCAT2 ( ortholog_one2one )
GuineaPig_ LPCAT2 ( ortholog_one2one )
Macaque_ LPCAT2 ( ortholog_one2one )
Mouse_ Lpcat2 ( ortholog_one2one )
Pig_ LPCAT2 ( ortholog_one2one )
Rat_ Lpcat2 ( ortholog_one2one )
Rabbit_ LPCAT2 ( ortholog_one2one )
OhnologsLPCAT1
ParalogsLPCAT4, LPCAT1, GPAT4, GPAT3
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs837550 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000269|PubMed:20363836, ECO:0000269|PubMed:21498505};
Single-pass type II membrane protein {ECO:0000269|PubMed:21498505}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q8BYI6};
Single-pass type II membrane protein {ECO:0000305|PubMed:21498505}. Cell membrane {ECO:0000250|UniProtKB:Q8BYI6};
Single-pass type II membrane protein {ECO:0000305|PubMed:21498505}. Lipid droplet {ECO:0000269|PubMed:21498505}.
Mouse PG classificationNA
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