| Gene Information | |
|---|---|
| Gene Name | LPCAT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 534 |
| Protein Names | Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1) (LPCAT-1) (LysoPC acyltransferase 1) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkenylglycerophosphocholine O-acyltransferase) (EC 2.3.1.25) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 2) (Phosphonoformate immuno-associated protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000153395 ) 3 ( ENSG00000275079 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NF37 |
| Gene Card | LPCAT1 |
| Uniprot ID | Q8NF37 |
| Pfam | PF01553; PF13833 |
| In ASD | no |
| Allosteric Prediction | no (-0.24091794) |
| Ortholog in Animals | Alpaca_ LPCAT1 ( ortholog_one2one ) Dog_ LPCAT1 ( ortholog_one2one ) GuineaPig_ LPCAT1 ( ortholog_one2one ) Macaque_ LPCAT1 ( ortholog_one2one ) Mouse_ Lpcat1 ( ortholog_one2one ) Pig_ LPCAT1 ( ortholog_one2one ) Rat_ Lpcat1 ( ortholog_one2one ) |
| Ohnologs | LPCAT2 |
| Paralogs | LPCAT2, LPCAT4, GPAT4, GPAT3 |
| Tissue | NA |
| Tissue Specificity | Erythrocytes. {ECO:0000269|PubMed:18156367}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:21498505}; Single-pass type II membrane protein {ECO:0000269|PubMed:21498505}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q3TFD2}; Single-pass type II membrane protein {ECO:0000305|PubMed:21498505}. Cell membrane {ECO:0000305|PubMed:18156367}; Single-pass type II membrane protein {ECO:0000305|PubMed:21498505}. Lipid droplet {ECO:0000269|PubMed:21498505}. Note=May adopt a monotopic topology when embedded in the lipid monolayer of the lipid droplet, with both termini exposed to the cytoplasm. {ECO:0000269|PubMed:21498505}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |