| Gene Information | |
|---|---|
| Gene Name | LPA |
| Organism | Homo sapiens (Human) |
| Gene Length | 2040 |
| Protein Names | Apolipoprotein(a) (Apo(a)) (Lp(a)) (EC 3.4.21.-) |
| Target Name | apolipoprotein(a) |
| Target Type | Clinical trial target |
| Gene Age | 36 ( ENSG00000198670 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | NA |
| Gene Card | LPA |
| Uniprot ID | P08519 |
| Pfam | PF00051; PF00089 |
| In ASD | no |
| Allosteric Prediction | yes (0.388039425) |
| Ortholog in Animals | Alpaca_ LPA ( ortholog_one2one ) Mouse_ Gm6619 ( ortholog_one2many ) Mouse_ 5430401F13Rik ( ortholog_one2many ) Rat_ Lpal2 ( ortholog_one2one ) |
| Ohnologs | HGF |
| Paralogs | PRSS56 |
| Tissue | liver |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1I71 (X-ray 1.45A ) 1JFN (NMR - ) 1KIV (X-ray 2.10A ) 2FEB (NMR - ) 3KIV (X-ray 1.80A ) 4BV5 (X-ray 2.10A ) 4BV7 (X-ray 1.70A ) 4BVC (X-ray 1.60A ) 4BVD (X-ray 1.68A ) 4BVV (X-ray 1.80A ) 4BVW (X-ray 2.00A ) 4KIV (X-ray 2.20A ) 6RX7 (X-ray 1.63A ) |
| DBSNP | rs41259144 rs7765803 rs7765781 rs41272110 rs41272112 rs41264308 rs1801693 rs1211014575 rs41265936 rs3798220 rs3124784 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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