Gene Information
Gene NameLPA
OrganismHomo sapiens (Human)
Gene Length2040
Protein NamesApolipoprotein(a) (Apo(a)) (Lp(a)) (EC 3.4.21.-)
Target Nameapolipoprotein a messenger rna
Target TypeClinical trial target
Gene Age36 ( ENSG00000198670 )
Evolutionary StageNA
AlphaFoldDBNA
Gene CardLPA
Uniprot IDP08519
PfamPF00051; PF00089
In ASDno
Allosteric Predictionyes (0.388039425)
Ortholog in AnimalsAlpaca_ LPA ( ortholog_one2one )
Mouse_ Gm6619 ( ortholog_one2many )
Mouse_ 5430401F13Rik ( ortholog_one2many )
Rat_ Lpal2 ( ortholog_one2one )
OhnologsHGF
ParalogsPRSS56
Tissueliver
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1I71  (X-ray  1.45A  1JFN  (NMR  1KIV  (X-ray  2.10A  2FEB  (NMR  3KIV  (X-ray  1.80A  4BV5  (X-ray  2.10A  4BV7  (X-ray  1.70A  4BVC  (X-ray  1.60A  4BVD  (X-ray  1.68A  4BVV  (X-ray  1.80A  4BVW  (X-ray  2.00A  4KIV  (X-ray  2.20A  6RX7  (X-ray  1.63A 
DBSNP rs41259144  rs7765803  rs7765781  rs41272110  rs41272112  rs41264308  rs1801693  rs1211014575  rs41265936  rs3798220  rs3124784 
Subcellular location [CC]NA
Mouse PG classificationNA
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