Gene Information
Gene NameP2RY14
OrganismHomo sapiens (Human)
Gene Length338
Protein NamesP2Y purinoceptor 14 (P2Y14) (G-protein coupled receptor 105) (UDP-glucose receptor)
Target Namep2y purinoceptor 14
Target TypeLiterature-reported target
Gene Age544 ( ENSG00000174944 )
Evolutionary StageEumetazoa
AlphaFoldDBQ15391
Gene CardP2RY14
Uniprot IDQ15391
PfamPF00001
In ASDno
Allosteric Predictionyes (0.801105414)
Ortholog in AnimalsAlpaca_ P2RY14 ( ortholog_one2one )
Dog_ P2RY14 ( ortholog_one2one )
GuineaPig_ P2RY14 ( ortholog_one2one )
Macaque_ P2RY14 ( ortholog_one2one )
Mouse_ P2ry14 ( ortholog_one2one )
Pig_ P2RY14 ( ortholog_one2one )
Rat_ P2ry14 ( ortholog_one2one )
Rabbit_ P2RY14 ( ortholog_one2one )
OhnologsNA
ParalogsGPR34, GPR171, PTAFR, P2RY13, GPR87, P2RY12
TissueNA
Tissue SpecificityHighest expression in the placenta, adipose tissue, stomach and intestine, intermediate levels in the brain, spleen, lung and heart, lowest levels in the kidney.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cell membrane;
Multi-pass membrane protein.
Mouse PG classificationNA
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