| Gene Information | |
|---|---|
| Gene Name | MYO18B |
| Organism | Homo sapiens (Human) |
| Gene Length | 2567 |
| Protein Names | Unconventional myosin-XVIIIb |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000133454 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8IUG5 |
| Gene Card | MYO18B |
| Uniprot ID | Q8IUG5 |
| Pfam | PF00063 |
| In ASD | no |
| Allosteric Prediction | no (-0.986439293) |
| Ortholog in Animals | Alpaca_ MYO18B ( ortholog_one2one ) Dog_ MYO18B ( ortholog_one2one ) GuineaPig_ MYO18B ( ortholog_one2one ) Macaque_ MYO18B ( ortholog_one2one ) Mouse_ Myo18b ( ortholog_one2one ) Pig_ MYO18B ( ortholog_one2one ) Rat_ Myo18b ( ortholog_one2one ) Rabbit_ MYO18B ( ortholog_one2one ) |
| Ohnologs | MYO18A |
| Paralogs | MYO3A, MYH10, TMF1, MYO7B, MYO1D, CCDC102B, MYH1, MYO19, MYO1C, MYH3, MYH7, MYO1A, MYO15A, MYH9, MYO18A, MYO1E, MYH14, MYH2, MYH15, MYO3B, CCDC102A, MYO5A, MYO1G, MYO1H, MYO5C, MYO9B, MYO7A, MYH7B, MYO5B, CGNL1, CGN, MYH11, MYO16, MYO10, MYH8, MYH6, MYO9A, MYO6, MYH4, CCDC158, MYO1B, MYO1F, MYH13 |
| Tissue | heart, skeletal.muscle, artery, left.atrium, left.ventricle, mitral.valve, pulmonary.valve, tongue, tricuspid.valve |
| Tissue Specificity | Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs133885 rs13058434 rs750078923 rs3859866 rs370187232 rs5761170 rs9624909 rs17704912 rs5761268 rs1429133479 rs35578357 rs695633 rs33928909 rs35370367 rs2236005 rs200567905 rs6004901 rs7284177 rs34875296 rs780180192 |
| Subcellular location [CC] | Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere. Note=Punctate pattern in undifferentiated myoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes. |
| Mouse PG classification | LPG |
| click here to return to the previous page | |