| Gene Information | |
|---|---|
| Gene Name | GABRG1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 465 |
| Protein Names | Gamma-aminobutyric acid receptor subunit gamma-1 (GABA(A) receptor subunit gamma-1) |
| Target Name | gamma-aminobutyric acid receptor subunit gamma-1 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000163285 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8N1C3 |
| Gene Card | GABRG1 |
| Uniprot ID | Q8N1C3 |
| Pfam | PF02931; PF02932 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000150788) |
| Ortholog in Animals | Alpaca_ GABRG1 ( ortholog_one2one ) Dog_ GABRG1 ( ortholog_one2one ) GuineaPig_ GABRG1 ( ortholog_one2one ) Macaque_ GABRG1 ( ortholog_one2one ) Mouse_ Gabrg1 ( ortholog_one2one ) Pig_ GABRG1 ( ortholog_one2one ) Rat_ Gabrg1 ( ortholog_one2one ) Rabbit_ GABRG1 ( ortholog_one2one ) |
| Ohnologs | GABRA3, GABRA1, GABRE, GABRG2, GABRA6, GABRG3, GABRA5 |
| Paralogs | CHRNB1, GABRR2, CHRNA6, CHRNB4, CHRNA4, GABRQ, HTR3E, CHRNA1, CHRNA3, GABRA5, GLRA2, HTR3B, GLRA1, GABRG3, GABRA2, GABRB3, GABRP, HTR3C, HTR3D, CHRNA7, CHRFAM7A, GABRD, GABRR1, CHRNA5, GABRA6, GABRA4, GLRA3, GABRE, CHRNE, GABRG2, CHRND, CHRNA2, CHRNA10, CHRNA9, GABRA3, HTR3A, ZACN, CHRNB3, CHRNB2, CHRNG, GABRR3, GABRB2, GABRB1, GABRA1, GLRB |
| Tissue | brain, cerebral.cortex, amygdala, caudate.nucleus, cerebellum, hippocampus, hypothalamus, nucleus.accumbens, putamen, substantia.nigra |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17852913 |
| Subcellular location [CC] | Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
| click here to return to the previous page | |