| Gene Information | |
|---|---|
| Gene Name | ULBP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 244 |
| Protein Names | UL16-binding protein 1 (ALCAN-beta) (NKG2D ligand 1) (N2DL-1) (NKG2DL1) (Retinoic acid early transcript 1I) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000111981 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9BZM6 |
| Gene Card | ULBP1 |
| Uniprot ID | Q9BZM6 |
| Pfam | PF00129 |
| In ASD | no |
| Allosteric Prediction | no (-1.037515825) |
| Ortholog in Animals | Alpaca_ ULBP1 ( ortholog_one2one ) Mouse_ Raet1d ( ortholog_many2many ) Mouse_ Raet1e ( ortholog_many2many ) Pig_ ULBP1 ( ortholog_one2one ) Rat_ Raet1l ( ortholog_many2many ) Rat_ Rrlt ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | HLA-B, HLA-E, HLA-A, HLA-F, HLA-G, HLA-C, MR1, AZGP1, MICA, HFE, MICB, ULBP2, RAET1L, RAET1G, ULBP3, RAET1E, FCGRT, CD1B, CD1A, CD1D, CD1C, CD1E |
| Tissue | NA |
| Tissue Specificity | Expressed in T-cells, B-cells, erythroleukemia cell lines and in a wide range of tissues including heart, brain, lung, liver, testis, lymph node, thymus, tonsil and bone marrow. Also found in fetal heart, brain, lung and liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6903584 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12782710}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:12782710}. Endoplasmic reticulum {ECO:0000269|PubMed:12782710}. Note=In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi. {ECO:0000269|PubMed:12782710}. |
| Mouse PG classification | NA |
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